Effects of lipoprotein(a) on the binding
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Eduardo AnglΓ©s-Cano; Laurence Hervio; Didier Rouy; C. Fournier; John M. Chapman;
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Article
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1994
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Elsevier Science
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English
β 907 KB
Molecular assembly of plasminogen and tissue-type plasminogen actwator (t-PA) at the surface of fibrin results in the generation of fibrin-bound plasmin and thereby in the dissolution of a clot. This mechanism is triggered by specific interactions of intra-chain surface lysine residues in fibrin wit