The critical role of toll-like receptor
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Istvan Hritz; Pranoti Mandrekar; Arumugam Velayudham; Donna Catalano; Angela Dol
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Article
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2008
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John Wiley and Sons
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English
โ 576 KB
The Toll-like receptor 4 (TLR4) that recognizes endotoxin, a trigger of inflammation in alcoholic liver disease (ALD), activates two signaling pathways utilizing different adapter molecules: the common TLR adapter, myeloid differentiation factor 88 (MyD88), or Toll/interleukin immuneresponse-domain-