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Enhanced expression of retinoic acid-metabolizing enzyme CYP26A1 in sunlight-damaged human skin

✍ Scribed by Makoto Osanai; Gang-Hong Lee

Book ID
113053234
Publisher
Springer
Year
2011
Tongue
English
Weight
510 KB
Volume
44
Category
Article
ISSN
0918-4287

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## Abstract **BACKGROUND:** CYP26A1, together with CYP26B1 and CYP26C1, are key enzymes of all‐__trans__ retinoic acid (RA) inactivation and their specific and restricted expression in developing embryos participate in the fine tuning RA levels. As RA is a critical regulator of gene expression duri