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Enhanced expression of haem oxygenase-1 by nitric oxide and antiinflammatory drugs in NIH 3T3 fibroblasts

✍ Scribed by Maria José Alcaraz; Aïda Habib; Marilyne Lebret; Christophe Créminon; Sylviane Lévy-Toledano; Jacques Maclouf

Book ID: 110004960
Publisher: Nature Publishing Group
Year: 2000
Tongue: English
Weight: 273 KB
Volume: 130
Category: Article
ISSN: 0007-1188
DOI: 10.1038/sj.bjp.0703281

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## Background Stimulation of C3H 10T1/2 murine fibroblasts with interferon-γ(IFN) and bacterial lipopolysaccharide (LPS) generates reactive oxygen and nitrogen species leading to DNA damage, lipid oxidation, and tocopherol oxidation. The tocopherols possess unique chemical and biological properties