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Enhanced estrogen-induced proliferation in obese rat endometrium

โœ Scribed by Qian Zhang; Qi Shen; Joseph Celestino; Michael R. Milam; Shannon N. Westin; Robin A. Lacour; Larissa A. Meyer; Gregory L. Shipley; Peter J.A. Davies; Lei Deng; Adrienne S. McCampbell; Russell R. Broaddus; Karen H. Lu


Book ID
113434006
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
810 KB
Volume
200
Category
Article
ISSN
1097-6868

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โœ Yusuke Hiraku; Naruto Yamashita; Meiko Nishiguchi; Shosuke Kawanishi ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 153 KB

Estrogen-induced carcinogenesis involves enhanced cell proliferation (promotion) and genotoxic effects (initiation). To investigate the contribution of estrogens and their metabolites to tumor initiation, we examined DNA damage induced by estradiol and its metabolites, the catechol estrogens 2-hydro