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Enhanced Dissolution and Stability of Lansoprazole by Cyclodextrin Inclusion Complexation: Preparation, Characterization, and Molecular Modeling

✍ Scribed by Yi Lu, Tao Guo, Jianping Qi, Jiwen Zhang, Wei Wu


Book ID
118276473
Publisher
Springer US
Year
2012
Tongue
English
Weight
505 KB
Volume
13
Category
Article
ISSN
1530-9932

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I H\_31p NMR spectroscopy and molecular dynamics (MD) have been used to investigate the myo-inositol 2-phosphate (MY2P) inclusion complex in ct-cyclodextrin (a-CD). From spectral analyses, it has not been possible to estimate the stoichiometric ratio of MY2P to o~-CD, however several geometrical con