Enhanced development of morphine tolerance in rats treated with 2-deoxy-d-galactose
โ Scribed by P. Richter; W. Pohle; G. Grecksch; K. H. Smalla; R. Jork; H. Matthies
- Publisher
- Springer
- Year
- 1991
- Tongue
- English
- Weight
- 751 KB
- Volume
- 104
- Category
- Article
- ISSN
- 0033-3158
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The influence of "learning" on the development of tolerance to the analgesic effect of morphine in rats was examined employing the hot plate procedure. A tested-reinforced (Tr) group and its yoked-control, a tested-non-reinforced (Tnr) group, received identical exposure to the testing procedure; the
Reduction in energy consumption is known to inhibit development of a variety of spontaneous, carcinogeninduced, and hormone-dependent cancers, but the mechanism or mechanisms by which this occurs remain unknown. We hypothesize that energy consumption may modulate development of estrogen-dependent ne
In a previous study, we found that treating transgenic Big Blue rats with the hepatocarcinogen N-hydroxy-2-acetylaminofluorene (N-OH-AAF) produced the same major DNA adduct in the target liver and the nontarget spleen lymphocytes and bone marrow cells, induced lacI mutants in the liver, and induced