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Enhanced detection of chromosomal abnormalities in chronic lymphocytic leukemia by conventional cytogenetics using CpG oligonucleotide in combination with pokeweed mitogen and phorbol myristate acetate

✍ Scribed by Natarajan Muthusamy; Heather Breidenbach; Leslie Andritsos; Joseph Flynn; Jeffrey Jones; Asha Ramanunni; Xiaokui Mo; David Jarjoura; John C. Byrd; Nyla A. Heerema

Book ID: 116332566
Publisher: Elsevier
Year: 2011
Tongue: English
Weight: 179 KB
Volume: 204
Category: Article
ISSN: 2210-7762
DOI: 10.1016/j.cancergen.2010.12.006

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## Abstract We performed a multicentric study to assess the impact of two different culture procedures on the detection of chromosomal abnormalities in 217 consecutive unselected cases with chronic lymphocytic leukemia (CLL) referred for routine analysis either at the time of diagnosis (__n__ = 172