Serum corticosterone levels were determined following administration of the cholinergic agonist arecoline (4 mg/kg) to rats selectively bred for differences in cholinergic function. The Flinders Sensitive Line (FSL) of rats exhibited both greater suppression of behavioural activity and enhanced elev
โฆ LIBER โฆ
Enhanced benzodiazepine responsiveness in rats with increased cholinergic function
โ Scribed by Salvatore Pepe; David H. Overstreet; Ann D. Crocker
- Book ID
- 113222797
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 436 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0091-3057
No coin nor oath required. For personal study only.
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The purpose of this study was to evaluate ABT-418, a recently developed isoxasole bioisostere of nicotine and cholinergic channel activator (ChCA), in rats trained to perform a delayed-response task, the Delayed Stimulus Discrimination Task (DSDT). In dose-effect studies, ABT-418 improved DSDT perfo