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Enhanced antitumoral activity of oncolytic herpes simplex virus with gemcitabine using colorectal tumor models

โœ Scribed by Shinichi Esaki; Fumi Goshima; Hiroshi Kimura; Shingo Murakami; Yukihiro Nishiyama


Book ID
115556573
Publisher
John Wiley and Sons
Year
2012
Tongue
French
Weight
977 KB
Volume
132
Category
Article
ISSN
0020-7136

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## Abstract Oncolytic herpes simplex virus (HSV) is currently in phase III clinical trials for development as a novel therapeutic agent against a broad range of human tumors. Although results have been promising, clinical outcome is likely to be compromised by intrinsic and acquired resistance to H