Enhanced Antitumor Effect of Recombinant Human Tumor Necrosis Factor in Combination with Recombinant Human Granulocyte Colony-stimulating Factor in BALB/c Mice
β Scribed by Maeda, Masahiro ;Watanabe, Naoki ;Tsuji, Naoki ;Tsuji, Yasushi ;Okamoto, Tetsuro ;Sasaki, Hiroyoshi ;Akiyama, Shinichiro ;Niitsu, Yoshiro
- Book ID
- 108579706
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1993
- Tongue
- English
- Weight
- 395 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0910-5050
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## Abstract Recombinant human granulocyte colonyβstimulating factor (rhGβCSF) and erythropoietin (rhEPO) were used to treat patients with aplastic anemia (AA). In terms of effects on erythrocyte recovery, the combined use of rhGβCSF and rhEPO showed a favorable response in 6 of 14 (42.9%) patients
Combinations of low dosages of purified recombinant human (rh) macrophagecolony stimulating factor (M-CSF; also termed CSF-1) and rh granulocyte-colony stimulating factor (G-CSF) were compared alone and in combination for their influence on the cycling rates and numbers of bone marrow and splenic gr