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Enhanced anti-HIV-1 activity of CC-chemokine LD78β, a non-allelic variant of MIP-1α/LD78α

✍ Scribed by Xiaomi Xin; Tatsuo Shioda; Atsushi Kato; Huanliang Liu; Yuko Sakai; Yoshiyuki Nagai

Book ID
117111298
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
203 KB
Volume
457
Category
Article
ISSN
0014-5793

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Diverging binding capacities of natural
Diverging binding capacities of natural LD78β isoforms of macrophage inflammatory protein-1α to the CC chemokine receptors 1, 3 and 5 affect their anti-HIV-1 activity and chemotactic potencies for neutrophils and eosinophils
✍ Sofie Struyf; Patricia Menten; Jean-Pierre Lenaerts; Willy Put; Anne D'Haese; Er 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 160 KB 👁 1 views

Recently, the LD78 g isoform of the CC chemokine macrophage inflammatory protein (MIP)-1 § was shown to efficiently chemoattract lymphocytes and monocytes and to inhibit infection of mononuclear cells by R5 HIV-1 strains. We have now demonstrated that after cleavage of the NH 2 -terminal Ala-Pro dip