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Enhanced active liposomal loading of a poorly soluble ionizable drug using supersaturated drug solutions

โœ Scribed by Modi, Sweta; Xiang, Tian-Xiang; Anderson, Bradley D.


Book ID
119291778
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
908 KB
Volume
162
Category
Article
ISSN
0168-3659

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โœ Nanda Gopal Sahoo; Ali Abbas; Zaher Judeh; Chang Ming Li; Kah-Hay Yuen ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 565 KB

A modified multifluid nozzle spray drier was used to prepare drug containing microparticles of a poorly water-soluble anti-malarial drug, artemisinin (ART) with the aim of improving its solubility. We investigated the spray drying of ART with maltodextrin (MD) via a full factorial experimental desig