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Engrailed-2 is down-regulated but also ectopically expressed in clear cell renal cell carcinoma

โœ Scribed by Lai, Cai-yong; Pan, Bin; Luo, Yun; Liang, Wei-bo; Chen, Jie; Ye, Dong-ming; Guo, Ji-Nan; Li, Li; Su, Ze-xuan


Book ID
121549967
Publisher
Springer
Year
2014
Tongue
English
Weight
827 KB
Volume
41
Category
Article
ISSN
0301-4851

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## Abstract DJโ€1 is as a novel regulator of the tumor suppressor PTEN with stimulatory effects on PI3Kโ€AKT/PKB signaling, one possible target of which is cMyc. The catalytic unit of the telomerase complex, hTERT, can be activated at different levels, including transcriptionally by cMyc and through