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Engineering the Polyproline II Propensity of a Class II Major Histocompatibility Complex Ligand Peptide

โœ Scribed by Unudurthi, Sathya Dev; Hotta, Kinya; Kim, Chu-Young


Book ID
125832444
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
838 KB
Volume
8
Category
Article
ISSN
1554-8929

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Binding interactions between peptides an
โœ Benjamin J. McFarland; Craig Beeson ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 464 KB

## Abstract The activation of helper T cells by peptides bound to proteins of the class II Major Histocompatibility Complex (MHC II) is pivotal to the initiation of an immune response. The primary functional requirement imposed on MHC II proteins is the ability to efficiently bind thousands of diff