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Engineering synthetic vaccines using cues from natural immunity

✍ Scribed by Irvine, Darrell J.; Swartz, Melody A.; Szeto, Gregory L.

Book ID
121324866
Publisher
Nature Publishing Group
Year
2013
Tongue
English
Weight
799 KB
Volume
12
Category
Article
ISSN
1476-1122

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## Abstract Engineered nanoparticles have been designed based on the self‐assembling properties of synthetic coiled‐coil lipopeptide building blocks. The presence of an isoleucine zipper within the lipopeptide together with the aggregating effects of an N‐terminal lipid drives formation of 20–25 nm