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Engineering of quorum-sensing systems for improved production of alkaline protease by Bacillus subtilis

✍ Scribed by H. Tjalsma; E.J. Koetje; R. Kiewiet; O.P. Kuipers; M. Kolkman; J. van der Laan; R. Daskin; E. Ferrari; S. Bron

Book ID: 108837527
Publisher: John Wiley and Sons
Year: 2004
Tongue: English
Weight: 238 KB
Volume: 96
Category: Article
ISSN: 1364-5072
DOI: 10.1111/j.1365-2672.2004.02179.x

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## Abstract **BACKGROUND:** Response surface methodology is used to build a predictive model of the combined effects of independent variables (pH, salt concentration starch and casein). The model was validated in a laboratory‐scale bioreactor for extracellular protease production from a newly isola