Engineering of pharmaceutical materials: An industrial perspective

✍ Scribed by Kwok Chow; Henry H.Y. Tong; Susan Lum; Albert H.L. Chow

• Book ID: 102912353
• Publisher: John Wiley and Sons
• Year: 2008
• Tongue: English
• Weight: 735 KB
• Volume: 97
• Category: Article
• ISSN: 0022-3549
• DOI: 10.1002/jps.21212

✦ Synopsis

Crystal engineering provides a rational approach to solving formulation, processing and product performance problems. This review discusses how the concept of crystal engineering can be judiciously utilized to manipulate the solid-state properties of drugs and excipients for successful pharmaceutical formulation and process development. Existing and emerging manufacturing as well as co-processing technologies being applied in the pharmaceutical industry are also presented together with selected examples of crystal form design, crystal form selection and crystal modifications for illustration purposes.