Engineering of coordinated up- and down-
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Elisabetta G.P. Prati; Mattia Matasci; Tobias B. Suter; Andre Dinter; Adriana R.
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Article
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2000
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John Wiley and Sons
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English
โ 199 KB
๐ 2 views
Production of O-linked oligosaccharides that interact with selectins to mediate cell-cell adhesion occurs in one segment of a branched glycan biosynthesis network. Prior efforts to direct the branched pathway towards selectin-binding oligosaccharides by amplifying enzymes in this branch of the netwo