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Engineering of complex polyketide biosynthesis — insights from sequencing of the monensin biosynthetic gene cluster

✍ Scribed by P F Leadlay; J Staunton; M Oliynyk; C Bisang; J Cortés; E Frost; Z A Hughes-Thomas; M A Jones; S G Kendrew; J B Lester; P F Long; H AI McArthur; E L McCormick; Z Oliynyk; C BW Stark; C J Wilkinson

Book ID
110050914
Publisher
Springer-Verlag
Year
2001
Tongue
English
Weight
238 KB
Volume
27
Category
Article
ISSN
1476-5535

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✍ Vesna Simunovic; Rolf Müller 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 314 KB

## Abstract It has been proposed that two acyl carrier proteins (ACPs)—TaB and TaE—and two 3‐hydroxy‐3‐methylglutaryl synthases (HMGSs)—TaC and TaF—could constitute two functional ACP‐HMGS pairs (TaB/TaC and TaE/TaF) responsible for the incorporation of acetate and propionate units into the myxovir