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Engineering of an N-acetylneuraminic acid synthetic pathway in Escherichia coli

✍ Scribed by Junhua Kang; Pengfei Gu; Yang Wang; Yikui Li; Fan Yang; Qian Wang; Qingsheng Qi

Book ID: 118507035
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 493 KB
Volume: 14
Category: Article
ISSN: 1096-7176
DOI: 10.1016/j.ymben.2012.09.002

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## Abstract An __Escherichia coli__ strain expressing three recombinant enzymes, i.e., cytidine 5′‐monophosphate (CMP) kinase, sialic acid aldolase and cytidine 5′‐monophosphate __N__‐acetylneuraminic acid (CMP‐NeuAc) synthetase, was utilized as a biocatalyst for the production of CMP‐NeuAc. Both r