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Engineering hematopoietic stem and progenitor cells from human pluripotent stem cells for modeling congenital anemias

โœ Scribed by Vo, Linda; Doulatov, Sergei; Macari, Elizabeth R.; Chou, Stephanie S.; Gupta, Manav; Godfrey, Michelle; McGrath, Katherine; Schlaeger, Thorsten; Zon, Leonard I.; Daley, George


Book ID
125820398
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
60 KB
Volume
42
Category
Article
ISSN
0301-472X

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The team of Liu et al. generated endoderm-derived human induced pluripotent stem (iPS) cells from primary hepatocytes. 1 However, they generated human iPS cells by using viral transgenes. 1 Clinical applications of human iPS cells require avoiding viral transgenes. On the other hand, the reprogrammi