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Engineering Cytochrome P450 Enzymes

✍ Scribed by Gillam, Elizabeth M. J.

Book ID: 118214342
Publisher: American Chemical Society
Year: 2008
Tongue: English
Weight: 301 KB
Volume: 21
Category: Article
ISSN: 0893-228X
DOI: 10.1021/tx7002849

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## Abstract The cytochrome P450 monooxygenase system (CYP) is a multigene superfamily of heme‐thiolate enzymes, which are important in the metabolism of foreign and endogenous compounds. Genetic variations, drug interactions, or pathophysiological factors can lead to reduced, absent, or increased e