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Engineering a Protein Scaffold from a PHD Finger

✍ Scribed by Ann H.Y. Kwan; David A. Gell; Alexis Verger; Merlin Crossley; Jacqueline M. Matthews; Joel P. Mackay

Book ID: 114329296
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 590 KB
Volume: 11
Category: Article
ISSN: 0969-2126
DOI: 10.1016/s0969-2126(03)00122-9

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## Abstract We report the identification of a novel human gene (__SPOC1__) which encodes a protein with a PHD‐finger domain. The gene is located in chromosomal region 1p36.23, a region implicated in tumor development and progression. RNA __in situ__ hybridization experiments showed strong __SPOC1__