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Energy transfer in the glutamate dehydrogenase-NADH binary complex and its relation to the binding of cofactor

โœ Scribed by Murray R. Summers; K.Lemone Yielding


Book ID
118308916
Publisher
Elsevier Science
Year
1970
Tongue
English
Weight
566 KB
Volume
223
Category
Article
ISSN
0005-2728

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We have carried out calculations on the relative free energy of binding of biotin and its S27A and W79A mutants to streptavidin. Consistent with earlier suggestions by Miyamoto and Kollman from free energy component analysis and recent experiments by Stayton and coworkers, the reduction in binding s