Using rapid kinetic techniques, we have determined the kinetics of zero-trans influx and equilibrium exchange of adenosine, and its uptake and in situ phosphorylation at 25OC in human erythrocytes which were pretreated with 2'-deoxycoformycin to inhibit deamination of adenosine. Both the K , and V,
Energy metabolism of human erythrocytes in psoriasis
β Scribed by Maria S. Goncharenko; Elen A. Kosenko; Yury G. Kaminsky
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 467 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0020-711X
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A simplified mathematical model of cell metabolism describing ion pump, glycolysis and adenylate metabolism was developed and investigated in order to clarify the functional role of the adenylate metabolism system in human erythrocytes. The adenylate metabolism system was shown to be able to functio
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## Abstract It is thought that glycolysis is the predominant energy pathway in cancer, particularly in solid and poorly vascularized tumors where hypoxic regions develop. To evaluate whether glycolysis does effectively predominate for ATP supply and to identify the underlying biochemical mechanisms