Optimizing energy functions for proteinβ
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Oz Sharabi; Chen Yanover; Ayelet Dekel; Julia M. Shifman
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Article
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2010
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John Wiley and Sons
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English
β 473 KB
## Abstract Protein design methods have been originally developed for the design of monomeric proteins. When applied to the more challenging task of proteinβprotein complex design, these methods yield suboptimal results. In particular, they often fail to recapitulate favorable hydrogen bonds and el