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Energetics, Conformation, and Recognition of DNA Duplexes Modified by Monodentate RuII Complexes Containing Terphenyl Arenes

✍ Scribed by Olga Novakova; Jaroslav Malina; Tereza Suchankova; Jana Kasparkova; Tijana Bugarcic; Peter J. Sadler; Viktor Brabec

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
549 KB
Volume
16
Category
Article
ISSN
0947-6539

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Energetics, Conformation, and Recognition of DNA Duplexes Modified by Methylated Analogues of [PtCl(dien)]+
✍ Olga Nováková; Jaroslav Malina; Jana Kašpárková; Anna Halámiková; Vladan Bernard 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 640 KB

## Abstract Monodentate DNA binding of [PtCl(dien)]^+^ (dien=diethylenetriamine) complexes may considerably affect the biophysical properties of DNA and consequently downstream cellular processes as a result of a large increase in the bulkiness of the nonleaving ligand by multiple methylation (see