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Energetic limits of phosphotransfer in the catalytic subunit of cAMP-dependent protein kinase as measured by viscosity experiments

โœ Scribed by Adams, Joseph A.; Taylor, Susan S.


Book ID
126176251
Publisher
American Chemical Society
Year
1992
Tongue
English
Weight
826 KB
Volume
31
Category
Article
ISSN
0006-2960

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โœ Shahriar Mobashery; Michael Doughty; E. T. Kaiser ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 610 KB

A peptide affinity inactivator, Ac-Leu-Arg-Arg-Ala-(BrAc)Om-Leu-Gly, was used as a tool t o probe for active site residues in the catalytic subunit of bovine CAMP-dependent protein kinase. The peptide inactivated the catalytic subunit in an active site-directed and monophasic manner with a first-ord