Approach to the determination of hydrate
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John P. Higgins; Steven M. Arrivo; Robert A. Reed
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Article
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2003
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John Wiley and Sons
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English
โ 330 KB
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Near-infrared (IR) spectroscopy is used for the rapid, nondestructive identification and quantitation of the hydrate form of drug compounds forming both single and multiple hydration states. Near-IR is shown to be useful in both bulk drug and in finished solid dosage forms. The capability of near-IR