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Endotoxin triggers the expression of an inducible isoform of nitric oxide synthase and the formation of peroxynitrite in the rat aorta in vivo

✍ Scribed by Csaba Szabó; Andrew L. Salzman; Harry Ischiropoulos

Book ID
115930709
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
316 KB
Volume
363
Category
Article
ISSN
0014-5793

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## Abstract Nitric oxide (NO) is a small molecule produced during the conversion of l-arginine to l-citrulline by NO synthase (NOS). Several isoforms of NOS exist, of which the Ca2+-independent, inducible NOS (iNOS or NOS2) is most prominently expressed by macrophages. iNOS activity and increased l