Endotoxin suppresses mouse hepatic low-d
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Wei Liao; Mats Rudling; Bo Angelin
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Article
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1999
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John Wiley and Sons
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English
β 152 KB
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Endotoxin provokes an inflammatory state in the infected host. C3H/HeJ mice are tolerant to endotoxin because of an Lps gene mutation. Recent studies have identified that this gene encodes the Toll-like receptor 4. Endotoxin also induces hyperlipidemia and suppresses hepatic low-density lipoprotein