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Endotoxin (LPS) Stimulates 4E-BP1/PHAS-I Phosphorylation in Macrophages

โœ Scribed by Michael W. Potter; Shimul A. Shah; Kimberly K. Elbirt; Mark P. Callery


Book ID
115636354
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
199 KB
Volume
97
Category
Article
ISSN
0022-4804

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## Abstract Endotoxin (i.e., lipopolysaccharide, LPS) impairs skeletal muscle protein synthesis. Although this impairment is not acutely associated with a decreased plasma concentration of total amino acids, LPS may blunt the anabolic response to amino acids. To examine this hypothesis, rats were i