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Endotoxin-induced arachidonic acid metabolism requires de novo protein synthesis and protein kinase C activation

✍ Scribed by Janet Geisel; James A. Cook; Keith A. Coffee; W. Curtis Wise; Perry V. Halushka


Book ID
115740756
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
456 KB
Volume
1085
Category
Article
ISSN
0005-2760

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Exposure of osteoblast-like MC3T3-El cells to sodium arsenite (arsenite) increased the level of heat shock protein 27 (hsp27). The effect of arsenite was dose-dependent in the range of 50 to 200 pM. Arsenite also stimulated arachidonic acid release dose-dependently in the range between 50 and 200 pM