Endothelin receptor A-specific stimulation of glomerular inflammation and injury in a streptozotocin-induced rat model of diabetes
β Scribed by M. A. Saleh; E. I. Boesen; J. S. Pollock; V. J. Savin; D. M. Pollock
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 411 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0012-186X
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RNA blots of total cellular RNA isolated from quiescent and endothelin (ET-1)stimulated normal rat kidney (NRK) cells demonstrated that ET-1 induced the expression of c-jun, jun B, and c-fos mRNA in a time-dependent manner with maximal expression of mRNA by 1 hr after the addition of ET-1. Five hund
## Abstract ## Background Adenosine A1 receptor (A1βAR) activation can lower plasma glucose in diabetic rats lacking insulin. We investigated the change in A1βAR gene expression in diabetic rats. ## Methods The incorporation of [Uβ^14^C]βglucose into glycogen was carried out to evaluate the effe