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Endothelin-I receptor antagonist for the treatment of pulmonary arterial hypertension in systemic sclerosis

✍ Scribed by John Varga


Publisher
Springer
Year
2003
Tongue
English
Weight
96 KB
Volume
5
Category
Article
ISSN
1523-3774

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Improvement of vascular endothelial func
✍ P. P. Sfikakis; C. Papamichael; K. S. Stamatelopoulos; D. Tousoulis; K. G. Fragi πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 102 KB πŸ‘ 2 views

## Abstract ## Objective Increased endothelin activity may play a role in the pathogenesis of vascular injury, a primary feature of systemic sclerosis (SSc; scleroderma). Our goal was to test the hypothesis that treatment with the oral endothelin receptor antagonist bosentan might improve vascular