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Endothelin generating pathway through endothelin1–31 in human cultured bronchial smooth muscle cells

✍ Scribed by Yoko Hayasaki-Kajiwara; Noriyuki Naya; Toshitake Shimamura; Takanori Iwasaki; Masatoshi Nakajima


Book ID
110004411
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
245 KB
Volume
127
Category
Article
ISSN
0007-1188

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## Abstract Insulin is known to cause an increase in endothelin‐1 (ET‐1) receptors in vascular smooth muscle cells (SMCs), but the effect of insulin‐like growth factor 1 (IGF‐1) on ET‐1 receptor expression is not known. We therefore carried out the present study to determine the effect of IGF‐1 on