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Endothelin binding sites in porcine-aortic and rat lung membranes

โœ Scribed by Sandip M. KANSE; Mohammad A. GHATEI; Stephen R. BLOOM


Book ID
115126324
Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
417 KB
Volume
182
Category
Article
ISSN
1432-1327

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Endothelin binding in human isolated lung membrane fractions revealed a single class of high affinity recognition sites with a Kd of 1.33 +/- 0.15 nM and a Bmax of 9.61 +/- 1.44 pmol/mg protein. Endothelin inhibited [125I]endothelin binding with a Ki of 1.90 +/- 0.15 nM whereas structurally unrelate