Endothelin association with cultured rat hepatic endothelial cells: functional characterization
β Scribed by Ann T Eakes; Stephen A.K Harvey; Merle S Olson
- Book ID
- 117350878
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 323 KB
- Volume
- 1359
- Category
- Article
- ISSN
- 0167-4889
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π SIMILAR VOLUMES
Circulating endothelin (ET) levels are elevated in conditions such as endotoxemia, hepatic ischemia-reperfusion injury, or orthotopic liver transplantation, and this potent peptide may contribute to hepatic athophysiology. We measured the surface binding of [' IIET-1 to rat Kupffer cells in primary
The effect of endothelin (ET) 1 on intracellular Ca 2Ψ transients in cultured rat hepatic stellate cells (HSCs) during transformation was studied by use of single-cell fluorescence. Regardless of the duration of HSC culture, ET-1 caused a BQ-123-sensitive but IRL-1038-insensitive elevation of [Ca 2Ψ