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Endothelin-1 stimulates cytosolic phospholipase A2 activity and gene expression in rat glomerular mesangial cells

✍ Scribed by Schramek, Herbert; Wang, Yizheng; Konieczkowski, Martha; Simonson, Michael S; Dunn, Michael J

Book ID: 109883916
Publisher: Nature Publishing Group
Year: 1994
Tongue: English
Weight: 941 KB
Volume: 46
Category: Article
ISSN: 0085-2538
DOI: 10.1038/ki.1994.464

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## Abstract Bradykinin (BK), an inflammatory mediator, has been shown to induce cytosolic phospholipase A~2~ (cPLA~2~) expression implicating in inflammatory responses in various cell types. However, the detailed mechanisms underlying BK‐induced cPLA~2~ expression in astrocytes remain unclear. RT‐P