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Endothelin-1 reduces lipid accumulation in human macrophages

✍ Scribed by M.R. Langenfeld; W. Jessup; D.S. Celermajer

Book ID
119740274
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
152 KB
Volume
9
Category
Article
ISSN
1443-9506

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## Abstract Endothelin‐1 (ET‐1), a potent proatherogenic vasoconstrictive peptide, is known to promote macrophage foam cell formation via mechanisms that are not fully understood. Excessive lipid accumulation in macrophages is a major hallmark during the early stages of atherosclerotic lesions. Cho