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Endothelin-1 receptors on cultured rat articular chondrocytes: regulation by age, growth factors, and cytokines, and effect on cAMP production

✍ Scribed by Habib Messai; Andrei Panasyuk; Abdel-Majid Khatib; Alain Barbara; Dragoslav R. Mitrovic

Book ID
114096014
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
346 KB
Volume
122
Category
Article
ISSN
0047-6374

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Endothelin-1 (ET-1), originally described as a vasoconstrictor, is now known to be involved in pathogenesis of various disorders including vascular, inflammatory, and fibrotic diseases. Recent studies suggest that mast cells are also involved in the same pathological conditions. In this study, we te