Endothelin-1 modulates angiotensin II in the development of hypertension in fructose-fed rats
โ Scribed by L. T. Tran; K. M. MacLeod; J. H. McNeill
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 394 KB
- Volume
- 325
- Category
- Article
- ISSN
- 0300-8177
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๐ SIMILAR VOLUMES
Factors that increase resistance to blood flow through the hepatic sinusoids when portal hypertension occurs in the absence of significant hepatic fibrosis are not completely understood. Experiments were designed to test the hypothesis that endothelin-1 (ET-1) is one of the humoral factors that incr
Angiotensin II plays a crucial role in the control of blood pressure, acting at AT 1 or AT 2 receptors, and can act as a potent vasoconstrictor of the peripheral vasculature inducing hypertrophy, hyperplasia, or both, in resistance arteries. The aim of the present study was to investigate whether th
Tumour blood flow modification following i.v. administration of angiotensin II (AT II, 0.19 nmol kg-' min-I) or endothelin-I (ET-I, I nmol kg-') was compared in the P22 carcinosarcomabearing BD9 rat and the HSN fibrosarcoma-bearing CBH/CBi rat using the tissue uptake of radiolabelled iodoantipyrine.