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Endothelin-1 inhibits adipogenesis: Role of phosphorylation of Akt and ERK1/2

✍ Scribed by Indranil Bhattacharya; Axel Ullrich


Book ID
118442007
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
548 KB
Volume
580
Category
Article
ISSN
0014-5793

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## Abstract Numerous studies have shown that mammalian target of rapamycin (mTOR) inhibitor activates Akt signaling pathway via a negative feedback loop while inhibiting mTORC1 signaling. In this report, we focused on studying the role of mTORC1 and mTORC2 in rapamycin‐mediated Akt and ERK phosphor