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Endothelin-1 Induces NAD(P)H Oxidase in Human Endothelial Cells

โœ Scribed by Nicole Duerrschmidt; Nico Wippich; Winfried Goettsch; Hans-Juergen Broemme; Henning Morawietz


Book ID
115585445
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
79 KB
Volume
269
Category
Article
ISSN
0006-291X

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Vascular endothelial cells are constantly subjected to pressure-induced cyclic strain. Reactive oxygen species (ROS) have been implicated in atherosclerosis and vascular remodeling. Recent evidence indicates that a vascular NAD(P)H oxidase may be an important source of ROS in both physiologic and pa