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Endothelin-1 induces intracellular [Ca2+] increase via Ca2+influx through the L-type Ca2+channel, Ca2+-induced Ca2+release and a pathway involving ETAreceptors, PKC, PKA and AT1 receptors in cardiomyocytes

✍ Scribed by QingHua Zeng; XingTing Li; GuoGan Zhong; WenJie Zhang; ChengWen Sun


Book ID
107349702
Publisher
Science in China Press (SCP)
Year
2009
Tongue
English
Weight
861 KB
Volume
52
Category
Article
ISSN
1674-7305

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## Abstract Studies with in‐vitro‐cultured neurons treated with amyloid‐β (Aβ) peptides demonstrated neuronal loss by apoptosis that is due, at least in part, to the perturbation of intracellular Ca^2+^ homeostasis. In addition, it was shown that an endoplasmic reticulum (ER)‐specific apoptotic pat