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Endothelin-1 in children with chronic renal failure

✍ Scribed by Isabelle Blazy; Michèle Déchaux; Marina Charbit; Danièle Brocart; Jean-Claude Souberbielle; Marie France Gagnadoux; François Guillot; Charles Sachs

Publisher: Springer
Year: 1994
Tongue: English
Weight: 521 KB
Volume: 8
Category: Article
ISSN: 0931-041X
DOI: 10.1007/bf00868258

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## Abstract The complex pathogenesis of chronic renal disease (CRD) depends on endothelin (ET) axis (ETs and ET receptors) and nitric oxide (NO) because of their vasoactive effects and their role in general modulation of vascular homeostasis. Various renal cells synthesize ETs and NO that play a si