𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Endothelialization of polymer surfaces

✍ Scribed by Absolom, D. R. ;Hawthorn, L. A. ;Chang, G.


Book ID
102874313
Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
925 KB
Volume
22
Category
Article
ISSN
0021-9304

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✦ Synopsis


The role that substrate surface properties play in influencing the extent of endothelialization of polymer surfaces has been investigated. For a wide range of polymer surfaces, the degree of endothelialization for both porcine and bovine endothelial cells is directly related to polymer surface tension: increased endothelialization occurring with increasing substrate surface tension. As a result of adsorption of the proteins in the culture media, the surface properties of the polymers are altered con-siderably. The protein-coated polymers were characterized by means of liquidliquid contact angle measurements under non-denaturing conditions. A striking correlation is observed between the degree of endothelialization and the measured dextran contact angle. The degree of endothelial cell spreading is not related to polymer surface tension. Cell morphology and extracellular matrix production, however, are influenced by substrate surface properties.


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