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Endothelial Von Willebrand factor regulates angiogenesis

โœ Scribed by Richard D. Starke; Koralia E. Paschalaki; Francesco Ferraro; Nicola H. Dryden; Thomas A.J. McKinnon; Rachel E. Sutton; Elspeth M. Payne; Dorian O. Haskard; Alun D. Hughes; Daniel F. Cutler; Mike A. Laffan; Anna M. Randi

Book ID
113952112
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
63 KB
Volume
56
Category
Article
ISSN
1537-1891

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Expression of von Willebrand factor, an
Expression of von Willebrand factor, an endothelial cell marker, is up-regulated by angiogenesis factors: A potential method for objective assessment of tumor angiogenesis
โœ Lucia Zanetta; Stuart G. Marcus; Julie Vasile; Michael Dobryansky; Henry Cohen; ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 230 KB

von Willebrand factor (vWF), a glycoprotein produced uniquely by endothelial cells and megakaryocytes, is routinely used to identify vessels in tissue sections. Vessel density in tumor specimens, as determined by immuno-histochemical staining for vWF or other endothelial cell markers, is a negative