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Endothelial expression of CXCR7 and the regulation of systemic CXCL12 levels

✍ Scribed by Berahovich, Robert D.; Zabel, Brian A.; Lewén, Susanna; Walters, Matthew J.; Ebsworth, Karen; Wang, Yu; Jaen, Juan C.; Schall, Thomas J.


Book ID
127065921
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
649 KB
Volume
141
Category
Article
ISSN
0019-2805

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## Abstract ## Objective CXCR4 is a chemokine with multiple effects on the immune system. In murine lupus models, we demonstrated that monocytes, neutrophils, and B cells overexpressed CXCR4 and that its ligand, CXCL12, was up‐regulated in diseased kidneys. We undertook this study to determine whe